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Introduction of Clinical Toxicology
Toxicology is defined as "the study of the adverse effects of chemicals or physical agents on living organisms."
It is traditionally known as "the science of poisons." A toxicologist is a scientist who determines harmful effects and the cellular, biochemical, and molecular mechanisms responsible.
Toxicology
Advance Toxicology
Vital signs (pulse rate, respiratory rate, temperature, blood pressure, oxygen saturation, capillary blood glucose, pain severity) are crucial in medical toxicology. They provide physiologic clues to toxicologic etiology and severity, and help monitor response to treatment.
Toxicology
Introduction to Toxicology - Study Notes
Toxicology is the study of how natural or man-made poisons cause undesirable effects in living organisms.
Toxicity: Describes the degree to which a substance is poisonous or can cause injury. Toxicity depends on: dose, duration and route of exposure, shape and structure of the chemical, and individual human factors.
Toxicology
Clinical Toxicology - Short Notes
Poison Definition: Any substance that can cause adverse effects to a living organism when exposed. Systemic poisoning requires absorption.
Toxicology
Toxicokinetics - Elements of Modern Toxicology
Toxicokinetics is the study of the absorption, distribution, metabolism, and excretion (ADME) of toxic parent compounds and their metabolites. It helps predict the concentration of toxin at the site of injury and resulting damage.
Toxicology
Heavy Metal Intoxication - Short Note
Heavy metal intoxication: Exposure via environment (water, food, utensils, cookware), occupational settings (mining, industry), pollution (fossil fuels, leaded gasoline). Metals exert toxicity by combining with reactive groups (ligands) essential for physiological functions: oxygen (-OH, -COO-), sulfur (-SH), nitrogen (-NH). Chelating agents are designed to compete for these metals, prevent/reverse toxicity, enhance excretion.
Toxicology
Clinical Toxicology - Short Note
Clinical toxicology deals with the assessment and treatment of persons exposed acutely or chronically to potentially harmful toxic chemicals. Optimal management requires an interdisciplinary approach due to the diversity of substances and clinical manifestations.
Toxicology
Basic Toxicology
Toxicologists are experts on poisons and poisoning. There is a movement for evidence-based toxicology as part of the larger movement towards evidence-based practices. Toxicology currently contributes to cancer research, since some toxins can be used as drugs for killing tumor cells (e.g., ribosome-inactivating proteins in leukemia treatment).
Toxicology