WATER HANDLING SYSTEM AT THE PRODUCTION PREMISES.

1.    Purpose: 

To lay down the procedure of Water handling system at the Production premises.  

2.    Scope: 

This SOP is applicable for the Production Area of  abc Pharmaceuticals Limited.

3.    Definition / Abbreviation:   

N/A.

4.    Responsibilities: 

The Roles and Responsibilities are as follows :
Roles    Responsibilities
Operator     •     To follow the laid down procedure.
Executive, Production    •     To monitor and check the laid down procedure.
Assistant Manager, Production    •    To implement this correctly.
Manager, Quality assurance    •    To approve the Document.

5.    Revision Details

Sl. No.    Version no.    Effective date    Change History

6.    Annexure:

N/A

7.        Procedure:

    Precaution :
•     During collection of hot water, wear heat resistance gloves.
•     Before collection check all the point of connection & ensure that no one is open.
•    Keep all inlet and outlet of circulating loop / storage tank and open ends of S.S. pipelines closed at the day end of work
•     Always keep the water off-take valves closed at every use point after use.
•     At the end of the day, ensure that no flexible hose pipe remains attached with the use point.
•     Potable water should not be use in manufacturing process.

7.1    Types :

Three types of water used in Manufacturing area.
1.    Potable Water
2.    Hot Water 
3.    Purified Water

7.2    Potable Water

7.2.1    Connect pipe with the potable water system.
7.2.2    Check availability of potable water in the line.
7.2.3    Collect potable water from potable water mark water line.
7.2.4    Use Pharma grade container to collect PW for cleaning purpose.
7.2.5    Transfer potable water to the respective production area by using SS trolley.
7.2.6    After completion of work hang the pipe on the hanger.
7.2.7    Keep both ends close with Alu foil after drain out of remaining water from pipe at the end of the day work.

7.3    Hot Water

7.3.1    Connect pipe with the hot water system.
7.3.2    Check availability of hot water in the line.
7.3.3    Collect hot water from hot water mark water line.
7.3.4    Use Pharma grade container to collect hot water for cleaning purpose.
7.3.5    Transfer hot water to the respective production area by using SS trolley.

7.4    Purified Water

7.4.1    Before Collection of purified water from the main re-circulation loop of purified water, connect the pipe with 50 Liter storage tank and main loop.
7.4.2    Collect the purified water into the storage tank by turning the valve open.
7.4.3    Circulate the water through the sectional circulation loop for 5 minutes and drain through use points and storage tank outlet.
7.4.4    Transfer purified water to the respective production area by using SS trolley.
7.4.5    After completion of work, disconnect the pipe between the pipe storage tank and main circulating loop and hang the pipe on the hanger.
7.4.6    Keep both ends close with Alu foil after drain out of remaining water from pipe at the end of the day work.