CVD Medicines | Graduate Pharmacy Notes
Pharmacological Treatment Strategies for Cardiovascular Conditions
Based on FIP Cardiovascular Handbook
Learning Objectives
- Design evidence-based pharmacological treatment plans for hypertension according to current guidelines
- Implement guideline-directed medical therapy for heart failure with reduced ejection fraction (HFrEF)
- Select appropriate lipid-lowering therapies based on cardiovascular risk and lipid parameters
- Develop antithrombotic regimens for various cardiovascular conditions considering bleeding risk
- Manage stable angina with appropriate antianginal therapies and secondary prevention strategies
- Monitor for adverse effects and drug interactions in complex cardiovascular pharmacotherapy
A. Pharmacological Treatment of Hypertension
Hypertension management follows evidence-based guidelines with specific recommendations for drug selection, combination therapy, and monitoring.
WHO Guidelines for Hypertension Treatment (2021)
- First-line therapy: Thiazide/thiazide-like diuretics, ACE inhibitors, ARBs, or long-acting CCBs
- Combination therapy: Recommended when monotherapy inadequate; prefer single-pill combinations
- Treatment goals:
